Voltage-clamp studies of the calcium inward current in an identified snail neurone: comparison with the sodium inward current.
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Voltage clamp analysis of two inward current mechanisms in the egg cell membrane of a starfish
Ionic mechanisms of excitation were studied in the immature egg cell membrane of a starfish, Mediaster aequalis, by analyzing membrane currents during voltage clamp. The cell membrane shows two different inward current mechanisms. One is activated at a membrane potential of -55 approximately -50 mV and the other at -7 approximately -6 mV. They are referred to as channels I and II, respectively....
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Dear Sir: Recently Lee et al. (1978) and Akaike et al. (1978) have published in this Journa l two very interest ing papers , repor t ing elegant exper iments with the internally per fused nerve cell bodies. We are especially happy with the success of these authors: the idea o f how simple it is to substitute the cytoplasm of the cell body by artificial saline has once more appeared to be frui t...
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Dear Sir: Recently Lee et al. (1978) and Akaike et al. (1978) have published in this Journa l two very interest ing papers , repor t ing elegant exper iments with the internally per fused nerve cell bodies. We are especially happy with the success of these authors: the idea o f how simple it is to substitute the cytoplasm of the cell body by artificial saline has once more appeared to be frui t...
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THE mechanisms of action of antiarrhythmic drugs were discussed in these reviews over a decade ago (Rosen and Hoffman, 1973). Since then, important new concepts of the blocking action of drugs have been proposed and tested experimentally. Several attempts at a quantitative voltage clamp analysis of the blocking action of antiarrhythmic drugs have been made. The mechanism of the blocking action ...
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The roles of cyclic nucleotide-gated (CNG) channels in sensory transduction have long been recognized. More recent studies found that CNG channels are distributed in multiple brain regions involved in memory and learning, including the cortex, hippocampus and cerebellum. These findings suggest that their functions are not limited to sensory perception, but also to neuronal plasticity phenomena,...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1975
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1975.sp011014